Protein Molecular Weight Markers
ABclonal Technology Adenosine Deaminase (ADA) Rabbit pAb
This gene encodes an enzyme that catalyzes the hydrolysis of adenosine to inosine in the purine catabolic pathway. Various mutations have been described for this gene and have been linked to human diseases related to impaired immune function such as severe combined immunodeficiency disease (SCID) which is the result of a deficiency in the ADA enzyme. In ADA-deficient individuals there is a marked depletion of T, B, and NK lymphocytes, and consequently, a lack of both humoral and cellular immunity. Conversely, elevated levels of this enzyme are associated with congenital hemolytic anemia.
ABclonal Technology SERPINA9 Rabbit pAb
Enables serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity. Predicted to be located in cytoplasm and membrane. Predicted to be active in extracellular space.
ABclonal Technology NDUFS4 Rabbit mAb
This gene encodes an nuclear-encoded accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I, or NADHubiquinone oxidoreductase). Complex I removes electrons from NADH and passes them to the electron acceptor ubiquinone. Mutations in this gene can cause mitochondrial complex I deficiencies such as Leigh syndrome. Alternative splicing results in multiple transcript variants.
ABclonal Technology GRK3 Rabbit mAb
The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function.
GenDEPOT Xpert Plus Prestained Protein Marker - Size: 500 ul
The Xpert Plus Prestained Protein Marker consists of a marker with 11 clearly identifiable bands at convenient molecular weights. The protein sizes are approximately 10, 14,18, 26, 36, 49, 64, 75, 110, 150 and 250 kDa, and this product has three reference bands.
The 26 kDa, 110 kDa reference bands, which have been recently improved, are orange, and 150 kDa reference band is purple. This marker is designed for monitoring protein separation during SDS-PAGE, verification of western transfer efficiency and approximate sizing of proteins.
ABclonal Technology ADAM19 Rabbit pAb
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has been demonstrated to be an active metalloproteinase, which may be involved in normal physiological processes such as cell migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction. It is proposed to play a role in pathological processes, such as cancer, inflammatory diseases, renal diseases, and Alzheimers disease.
ABclonal Technology MCM3 Rabbit pAb
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Several transcript variants encoding different isoforms have been found for this gene.
ABclonal Technology MCCC2 Rabbit pAb
This gene encodes the small subunit of 3-methylcrotonyl-CoA carboxylase. This enzyme functions as a heterodimer and catalyzes the carboxylation of 3-methylcrotonyl-CoA to form 3-methylglutaconyl-CoA. Mutations in this gene are associated with 3-Methylcrotonylglycinuria, an autosomal recessive disorder of leucine catabolism. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Sigma Aldrich Fine Chemicals Biosciences Gel filtration Markers Kit
Gel filtration markers kit contains five vials of proteins and 1 vial of blue dextran for calibration.
ABclonal Technology RBM5 Rabbit pAb
This gene is a candidate tumor suppressor gene which encodes a nuclear RNA binding protein that is a component of the spliceosome A complex. The encoded protein plays a role in the induction of cell cycle arrest and apoptosis through pre-mRNA splicing of multiple target genes including the tumor suppressor protein p53. This gene is located within the tumor suppressor region 3p21.3, and may play a role in the inhibition of tumor transformation and progression of several malignancies including lung cancer.
ABclonal Technology MRPS15 Rabbit mAb
This gene encodes a 28S mitochondrial ribosomal protein from the S15P family, involved in mitochondrial protein synthesis. Mitoribosomes, made of 28S and 39S subunits, differ from prokaryotic ribosomes by having more protein than rRNA and lacking 5S rRNA. Mitoribosomal proteins vary widely across species, making them hard to identify by sequence. This protein is over twice the size of its E. coli counterpart, though 12S rRNA binding sites are conserved. It is the least conserved small subunit protein between humans and mice. Pseudogenes are located on chromosomes 15q and 19q.
ABclonal Technology TMEM25 Rabbit pAb
Predicted to be involved in negative regulation of excitatory postsynaptic potential and regulation of protein stability. Predicted to be located in late endosome and lysosome.
Cayman Chemical CItrulntd Myeln BasIc Pr 500uL
An orally bioavailable broad-spectrum triazole antifungal agent completely inhibits growth of T. rubrum M. audouini M. canis and T. verrucosum as well as some C. albicans and A. fumigatus strains and other fungi (100 g/ml) bacteriostatic against E. coli P. aeruginosa S. aureus and S. pyogenes (100 g/ml) eliminates vaginal C. albicans candidiasis infection in 97 of rats (1 topical) eliminates vaginal C. albicans candidiasis infection in 50 of rats (10 mg/kg oral) decreases synthesis of 14a-desmethyl sterols and increases synthesis of methylated sterols in C. albicans (IC50 3 nM)